Membranoproliferative Glomerulonephritis

نویسندگان

  • Matthew C. Pickering
  • Joshua M. Thurman
چکیده

Membranoproliferative glomerulonephritis (MPGN) refers to glomerular pathology in which there is thickening of the capillary wall together with mesangial expansion. In this article we firstly review the pathological features of MPGN and discuss how advances in our understanding of the association between abnormalities in the regulation of complement and MPGN have revealed limitations in the historical pathological sub-division of MPGN. Secondly we review the clinical presentation of MPGN, its prognosis and therapeutic considerations.

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تاریخ انتشار 2012